This information is based of the research of Dr. J. Frederic Templeman, M.D.
"Let Food Be Your medicine" -- Hippocrates
Here is a list of medical conditions that Dr. Templeman uses mangosteen and xanthones contained within the fruit as first line treatment in his medical practice:
ERD (gastro-esophageal reflux disease)
Hiatal hernia
Diverticulitis
Arthritis
Sleep disorders
Irritable bowel disease (diarrheal type)
Fibromyalgia
Neurodermatitis
Fatigue
Eczema
Mild depression
Muscle or joint pain without evidence of Arthritis
Seborrhea
Recurrent urinary tract infections in the elderly
Here is a list of prescription medications that Dr. Templeman has replaced with mangosteen and xanthones:
Nexium, Prevacid, Aciphex, & other proton pump inhibitors.
Zantac, Pepcid, & other H2 blockers.
Allegra, Zyrtec, Claritin, Clarinex, & other antihistamines.
Singulair, Prednisone
Lotrisone, Topicort, Cutivate, Diprolene, & other topical Cortico Steroids used for skin conditions (Eczema, Psoriasis, Seborrhea)
Valium, Xanax, & other minor tranquilizers.
Tegretol, Neurontin, & other anti-epileptic drugs used (off label) for chronic pain relief.
Prozac, Zoloft, Paxil, Lexapro, & other antidepressants when used for Dysthymia & anxiety states.
Vicodin, Percocet, Duragesic patch, Methadone, & other narcotics used for chronic pain control.
Celebrex, Vioxx, Bextra, Naproxen, Arthrotec, Ibuprofin, & other anti-inflammatories used for Musculo-Skeletal pain & inflammation.
Ultram, Talwin, & other non-Opiod pain preparations.
Lipitor, Zolor, Pravacol, & other Lipid-lowering agents.
Valtrex, & other anti-herpetic agents.
Aricept, Cognex, & other Alzheimer’s preparations.
Anusol, & other Hemorrhoid preparations
VEMMA the best resource I've found
Medical Properties of Xanthones:
Research on Xanthones is ongoing. There are many results people report about health benefits from xanthones that cannot be explained by the science yet. This is likely due to the fact that only about 15% of known xanthones have been studied to any degree.
Some of the known benefits of xanthones based on recent research are:
Anti-Fatigue - Helps boost energy.
Anti-Inflammatory - Helps prevent and reduce inflammation
Anti-Aging
Helps prevent cancer. According to a preliminary study, six xanthones have been found to be capable of killing cancer cells.
Helps lower blood pressure
Helps lower blood sugar. Many people with type II diabetes have reported that it helps them to regulate their blood sugar levels.
Anti-Diarrheal - In folk medicine, the pericarp of the mangosteen (most potent source of xanthones) has been used for centuries to effectively treat dysentery.
A recent study has confirmed that gamma mangostin, a xanthones derivative found in the mangosteen, is a potent COX (Cyclooxgenase) 2 inhibitor. The COX 2 enzyme is a chemical in the body that causes inflammation. This enzyme is commonly found in people suffering from joint pain and arthritis. However, it is also being found with other diseases as well, that are not as obvious, such as Parkinson's, Alzheimer's, cancer, and Diabetes. In three separate studies, a xanthones derivative of the mangosteen slowed down the body's production of the COX 2 enzyme.
List of Xanthones in Mangosteen
Here is a list of all of the xanthones found in mangosteen that have been named. There are others that have not been named yet that I have not included in this list. Currently, there are 43 xanthones known to be in the mangosteen.
Concerning the popular supplement Vemma, which contains the entire mangosteen fruit. It is safe to assume that this would also be a list of xanthones in Vemma:
BR-xanthone A BR-xanthone B Calabaxanthone Garcinone A Garcinone B Garcinone C Garcinone D Garcinone E Gamma-Mangostin Garcimangosone A Garcimangosone B Garcimangosone C 1-Isomangostin 3-Isomangostin 1-Isomangostin hydrate 3-Isomangostin hydrate Gartanin Demethylcalabaxanthone Maclurin Mangostenone Mangostanin Mangostanol Mangostin Mangostinone Mangostinone A Mangostinone B a-Mangostinb-Mangosting-Mangostin Norathriol Tovophyllin Tovophyllin A Tovophyllin B Trapezifolixanthone